Study finds out that treatment for MRSA may make it worse, find out how!
MRSA is a deadly bacterial infection that causes severe infection on a person’s body. Earlier, the infective bacteria were treatable by regular dosage of antibiotics.
But now, it has been found out that the MRSA bacteria has morphed itself into an unbeatable bacterium, capable of fighting even the strongest of antibiotic treatments, which are administered to cure the infection.
But a new finding by a medical center, has explored that the bacterial infection has developed so far, that it is making the antibiotics act against the body. Here are the details of the findings and its effects.
1 What is MRSA?
Methicillin-resistant Staphylococcus Aureus (MRSA) is an infection caused by a staph like bacteria. This staph bacterium is a kind of bacteria that has become resistant to the normal type of antibiotics.
There are 2 type of MRSA- health care associated MRSA (HA-MRSA) and community associated MRSA (CA-MRSA). HA-MRSA is caused when patients are in hospital care like nursing homes or dialysis centers. HA-MRSA infections are usually associated with invasive procedures like surgeries, IV tubing or artificial joints.
Whereas CA-MRSA is caused when patient has been in a community setting. This infection might begin as a painful boil on the skin. It can also spread via skin to skin contact.
2 Treatment for MRSA
Treatment for MRSA, surprisingly is still antibiotics. Yes, even the relative strains of MRSA are still treatable by antibiotics.
In some cases, even the antibiotics are also not necessary. The doctors may use surgical procedures to drain out the superficial abscess from the boils which are caused by MRSA and this makes the bacteria go away.
3 The new Study
A research study conducted by Dr. George Liu of the Cedars-Sinai Medical Center and his team found that the antibiotics used for treating the MRSA, are actually making things worse.
MRSA is known to cause more than 80,000 infections and 11,000 deaths every year and it has developed resistance to most antibiotics, that are used to treat the disease. Most common antibiotics that are given to the patients in treatment, may unintentionally trigger the body’s own pathogen-defense system and worsen MRSA skin infections.
4 Finding of the study
The study finds that patients who have MRSA, receive beta-lactum antibiotic to treat the infection, and they may actually end up feeling sicker than usual. “Our findings underscore the urgent need to improve awareness of MRSA and rapidly diagnose these infections to avoid prescribing antibiotics that could put patients’ lives at risk,” Liu said.
In the study, the scientists gave high number of MRSA bacteria to the mice, causing an infection. Then the mice were given beta-lactum antibiotics for treatment, which resulted in them become even more sicker.
5 MRSA developing resistance to the treatment
Normally beta-lactum kills the MRSA bacteria. But MRSA started developing a new strain of protein that was somewhat affected by the antibiotics and is now less effective in building a cell wall like a normal protein.
So the MRSA ends up building a weak cell wall and the body’s immune system detects this anomaly, reacting aggressively and attacking the weak cell wall. “In situations where there is a lot of infection, this highly aggressive response can cause extensive inflammation and tissue damage, effectively making the consequences of the infection worse,” Liu said.
This is now causing a problem for the physicians because their first line of defense against staph and MRSA is treating patients with beta-lactum antibiotics. But these new findings have put a dampener on their treatment process, since the antibiotics which were very effective, are now known to make the condition worse.